de Paula Silva Lalucci, Marielle Priscilade Souza Marques, Déborah CristinaCaroline Santos, IsabellaZirondi Caitano, JéssicaFerrari Silva, BrunoValdés-Badilla, PabloMagnani Branco, Braulio Henrique2023-09-142023-09-142023-03-231989-208X10.12873/431silvahttps://hdl.handle.net/20.500.12536/2061Introduction: Obesity in adolescence is associated with severe health complications. Objective: To analyze possible associations among body mass index (BMI), body composition, and biochemical profiles of overweight or obese adolescents. Methods: The study was carried out between 2017 and 2020 and included 132 adolescents aged 10 to 18 years. The following variables were analyzed: BMI, fat-free mass (FFM), body fat mass (BFM), skeletal muscle mass (SMM), body fat percentage (%BF), waist-to-hip ratio (WHR), lean mass index (LMI), fat mass index (FMI), and fat-to-lean mass ratio (FMR), as well as total cholesterol (TC), high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c) and glutamic-oxaloacetic transaminase (TGO). Statistical analyses were performed using SPSS® version 20.0, considering p<0.05 as significant. Results: Higher values were identified for height, LBM, FFM, and SMM in the male group. On the other hand, higher values were identified for the %BF and FMI in the female group. The female, male, and general groups showed significant correlations between BMI and FMR (r = 0.69, 0.74, and 0.69, respectively), BMI and FFM (r = 0.44, 0.67, and 0.49, respectively), BMI and SMM (r = 0.44, 0.68, and 0.50, respectively), and BMI and %BF (r = 0.40, 0.54, and 0.47, respectively). In the general group, BMI and HDL levels were correlated (r = −0.18; p=0.04). The BFM and WHR showed a predictive effect for TC; WHR and %BF showed a predictive effect for LDL concentrations, and %BF had a predictive effect for TGO (p<0.05). Conclusions: It was possible to verify that BMI, body composition, and biochemical measures show an interrelationship between them, such as with a worsening of anthropometric and body composition indicators associated with worst biochemical parameters, e.g., lower HDL-c and higher TC, LDL-c, and TGO. Thus, public policies are indispensable for combating obesity and related comorbidities in the early phases of life.enDelivery of Health CareAdolescent healthObesityBiomarkersCardiometabolic Risk FactorsInterrelationship among body mass index, body composition, and biochemical profiles of overweight adolescents in south of Brazil: A cross-sectional study.Artículo de revista