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The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons

Flores-Muñoz, Carolina; García-Rojas, Francisca; Pérez, Miguel A.; Santander, Odra; Mery, Elena; Ordenes, Stefany; Illanes-González, Javiera; López-Espíndola, Daniela; González-Jamett, Arlek M.; Fuenzalida, Marco; Martínez, Agustín D.; Ardiles, Álvaro O. (2022-11-17)

Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic ...